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Aldactone (Spironolactone)
One of the main functions of the kidneys is to retain salt (sodium chloride) and water. In patients with heart failure and cirrhosis, increased levels of a hormone produced by the adrenal glands, called aldosterone, causes salt and fluid retention by the kidneys. Spironolactone inhibits the action of aldosterone causing the kidneys to excrete salt and fluid while retaining potassium. Therefore, spironolactone is classified as a potassium-sparing medication that promotes the output of urine (diuretic).
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One of the main functions of the kidneys is to retain salt (sodium chloride) and water. In patients with heart failure and cirrhosis, increased levels of a hormone produced by the adrenal glands, called aldosterone, causes salt and fluid retention by the kidneys. Spironolactone inhibits the action of aldosterone causing the kidneys to excrete salt and fluid while retaining potassium. Therefore, spironolactone is classified as a potassium-sparing medication that promotes the output of urine (diuretic).